A mathematical model for using fuzzy Weibull distribution for the effect of Cisplatin on lung cancer cell

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Abstract

The reaction of cisplatin on the cell cycle and DNA synthesis of human lung adenocarcinoma cell line $P C-9$ were analysed by flow cytometry by exposure to cisplatin $(1.0 \mu \mathrm{g} / \mathrm{ml})$ for 1 and 24 hours revealed a delayed $S$-phase transit and an gathering of cells in the $G 2 / M$-Phase. Two type of treatment have been studied with fuzzy failure rate function using fuzzy Weibull distribution.

Keywords:

Failure time, fuzzy weibull distribution, PC-9 cell, cell cycle, DNA synthesis rate

Mathematics Subject Classification:

Mathematics
  • K. Radhika P.G and Research Department of Mathematics, Rajah Serfoji Government College (Autonomous) [Affiliated to Bharathidasan University, Tiruchirappalli-620024, Tamil Nadu, India.], Thanjavur-613005, Tamil Nadu, India.
  • C. Alexander P.G and Research Department of Mathematics, Raja Doraisingam Government Arts College [Affiliated to Alagappa University, Karaikudi, Tamil Nadu, India.], Sivagangai-630561, Tamil Nadu, India.
  • S. Anbalagan P.G and Research Department of Mathematics, Rajah Serfoji Government College (Autonomous) [Affiliated to Bharathidasan University, Tiruchirappalli-620024, Tamil Nadu, India.], Thanjavur-613005, Tamil Nadu, India.
  • Pages: 101-104
  • Date Published: 01-01-2021
  • Vol. 9 No. 01 (2021): Malaya Journal of Matematik (MJM)

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Published

01-01-2021

How to Cite

K. Radhika, C. Alexander, and S. Anbalagan. “A Mathematical Model for Using Fuzzy Weibull Distribution for the Effect of Cisplatin on Lung Cancer Cell”. Malaya Journal of Matematik, vol. 9, no. 01, Jan. 2021, pp. 101-4, https://www.malayajournal.org/index.php/mjm/article/view/978.